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Carcinogenesis In a very lifetime carcinogenicity study completed in B6C3F1 mice, methylphenidate induced a rise in hepatocellular adenomas, and in males only, a rise in hepatoblastomas in a day by day dose of close to 60 mg/kg/day. This dose is close to 2 periods the MRHD of 60 mg/working day supplied to youngsters on mg/m2 basis.The Lively compon